​​​​​​​January 2019, Vol. 4, No 1, pp 1-8. 

​​Effects of Lifestyle on Fertility in Women with Polycystic Ovarian Syndrome

P. Mounika*, R. Mounika Vinusha, K. Raj Kiran
Department of Pharmacy Practice, Vignan Institute of Pharmaceutical Technology,Visakhapatnam, Andhra Pradesh, India - 530049.
​​*Corresponding author’s e-mail: mounicapedada@gmail.com

Abstract

Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders affecting reproductive age women worldwide. Women with PCOS experience absent or infrequent menses, infertility, acne, and excess hair growth, and ultrasound images show enlarged multicystic ovaries. Symptoms of PCOS include the endocrine system and reproductive signs which occur in the shape of amenorrhea or oligomenorrhea, hirsutism, obesity, acne, male pattern hair loss and reproductive disorders. IR is found in women with PCOS irrespective of their weight though it is more common with increasing weight and waist circumference (WC), which is especially significant as PCOS women are more likely to be overweight and have central obesity compared to the general population. Overweight and obesity affect reproductive capacity in the general population as well as in subfertile couples. Ovulatory subfertile women with a body mass index (BMI) of 29 kg/m2 or higher than 29kg/m2 have 4% lower pregnancy rate per kg/m2 increase per year, compared to ovulatory subfertile women with a BMI below 29. Lifestyle modification is widely accepted as a first line of treatment for women with PCOS to optimize their health before and after with any fertility treatment. Weight loss and lifestyle management have been shown to improve mood states and reduce depressive symptoms in overweight and obese women without PCOS. This provided evidence that although weight loss is important, dietary composition may also be an influencing factor.

Keywords: Polycystic ovarian syndrome; Obesity; Fertility; Lifestyle.

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