International Journal of Modern Science and Technology, Vol. 2, No. 4, 2017, Pages 179-187.
Synthesis, structural and biological studies of complexes of Ti (III) with different Schiff bases
G. Nizami*, S. Ahmad, A. Akhtar
Department of Chemistry, Sir Syed Faculty of Science, Bareilly College Bareilly (UP) 243005. Mohammad Ali Jauhar University, Rampur (UP) 244901. India.
*Corresponding author’s e-mail: firstname.lastname@example.org
The complexes of Ti (III) are prepared with the proposed ligands (5-Methyl2hydroxyacetophenonemorpholine-N- thiohydrazone, 5-Methyl2-hydroxyacetophenone antipyrine, 5-Methyl 2-hydroxyacetophenonethiosemicarbazone, 2-Hydroxy 5-chloro acetophenonemorpholine-N- thiohydrazone and 2-Hydroxy 5-chloro acetophenone, thiosemicarbazone). These ligands synthesized by the corresponding amino compounds and carbonyl compounds are characterized by molar conductivity, elemental analyses, magnetic susceptibility, electronic spectra, visible spectra, IR spectra and TGA. The adducts have been characterized on the basis of elemental analyses,molar conductance,IR, visible spectra, magnetic susceptibility measurement and TGA. The ligands behave in dibasic Tridentate manner in 5-Methyl2hydroxyacetophenonemorpholine-N- thiohydrazone and 2-Hydroxy 5-chloro acetophenonemorpholine-N- thiohydrazone . while 5-Methyl2-hydroxyacetophenone antipyrine behaves in monobasic tridentate manner and 2-Hydroxy 5-chloro acetophenone, thiosemicarbazone and 5-Methyl 2-hydroxyacetophenonethiosemicarbazone behave in tribasic bidentate manner . All the complexes were paramagnetic and have octahedral geometry. The free ligands and their metal complexes have been screened for their in vitro biological activities against bacteria, fungi and yeast. The metal complexes show more potent activities compared with Schiff base ligands.
Keywords: Molar conductivity; Elemental analyses; Magnetic susceptibility; Octahedral geometry; Paramagnetic character.
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