ISSN 2456-0235

International Journal of Modern Science and Technology

INDEXED IN 

International Journal of Modern Science and Technology, 1(5), 2016, Pages 183-192. 


Augmentation of Antimicrobial Behaviour of Silver Nanoparticles usingalpha-Cyclodextrin as Encapping Agent 

S. Lizy Roselet, J. PremaKumari
Department of Chemistry and Research Centre, Scott Christian College (Autonomous), Nagercoil-629003. India..

Abstract
This work reports a simple, novel, cost effective and eco-friendly synthesis of silver nanoparticles (AgNPs) using a-cyclodextrin as the reducing agent. Here a-cyclodextrin act as reducing agent as well as capping agent. This involves synthesis of silver nanoparticles by capping with different concentrations of a-cyclodextrin. The synthesized nanoparticles were characterized using Ultraviolet Visible spectroscopy (UV-VIS), X-ray Diffraction studies (XRD), Fourier Transform Infra Red (FT-IR) Spectroscopy and Transmission Electron Microscopy (TEM). UV-VIS Spectroscopy and X-ray diffraction studies confirmed the formation of nanoparticles. FT-IR Spectroscopy confirmed the binding of a-cyclodextrin to the AgNPs. Transmission electron microscopic studies also reveal the existence of spherical shaped particles of nano dimension. Antibacterial and antifungal activities of uncapped and capped AgNPs were investigated. It was found that capped AgNPs exhibited more antibacterial activity and antifungal activity when compared to the uncapped one. The capping with a-cyclodextrin showed much pronounced enhancement in antibacterial and antifungal behaviour in silver nanoparticles. a-cyclodextrin encapsulated AgNPs ensures its potential ability as an antimicrobial agent for therapeutic purposes as well as for antimicrobial coating materials.

​​Keywords: ​Silver nanoparticles; a-Cyclodextrin; Capping agent; Antibacterial activity; Antifungal activity.

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